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This page is dedicated to an overview of publications at the Metabolism Lab and up-to-date article collections related to our research themes.

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  1. Eimeria infections of plateau pika altered the patterns of temporal Z Tan, R Wang, Y Zhang, B Tang… - Insights in Microorganisms …, 2025 - books.google.com Tuesday 29 April 2025 And quickly frozen with liquid nitrogen for storage. After the with parasite-modified energy metabolism patterns. The change in diet from diverse plants in the field to simple
  2. Effects of tillage methods on soil aggregate nematode community in fluvo-aquic soil area of North China. R HU, X SHEN, S WANG, P FAN, B TAN… - Chinese Journal of …, 2025 - cje.net.cn Thursday 10 April 2025 In small mega-aggregates (2-5 mm), and decreased that of plant-parasitic nematodes matter was dominated by bacteria. Soil organic carbon, total nitrogen content, and
  3. iocontrol Strategies for Sustainable Management of Root-Knot Nematodes M Sharma, S Devi, S Chand - Physiological and Molecular Plant Pathology, 2024 - Elsevier Saturday 21 December 2024 The most damaging plant-parasitic nematodes globally. is the use of plant growth-promoting microbes (PGPM)- and iron, fixing nitrogen, producing phytohormones,
  4. Effect of soil moisture on nematode abundance and composition is modulated by determinism in community assembly in a savanna H Lei, N Lin, J Zhang, C Hou, C Yue, Y Chen, J Wu - Ecology, 2025 - authorea.com Thursday 27 March 2025 Variation in precipitation and microbial biomass carbon diversity was primarily controlled by soil nitrogen and impacted bacterivores and plant parasite diversity. At the
  5. A REVIEW OF THE EFFECT OF SOME PLANT BACTERIA ON GROUNDNUT PLANT IN NIGERIA MA Njobdi, UJ Hasiya - 2024 - digitallibrary.aun.edu.ng Thursday 07 November 2024 These bacteria suppress pathogenic microbes through by fungi, bacteria, and nematodes, thereby contributing to Nitrogen-fixing bacteria are integral to the nitrogen cycle
  6. Unearthing the hidden dangers by soil borne diseases of nursery plants: A review R Longjam, A Kotiyal, V Johar - Environment Conservation …, 2024 - journal.environcj.in Wednesday 31 July 2024 As excessive moisture and nitrogen availability can give , apart from viruses and plant parasitic nematodes, soil as insect pests or plantdamaging microorganisms, can
  7. elatonin as a modulator of MAPK cascade and ROS-RNS feedforward loop during plant pathogen interaction S Mansoor, I Farooq, OA Wani, P Ahmad… - … and Molecular Plant …, 2024 - Elsevier Saturday 27 July 2024 , bacteria, viruses, viroids, phytoplasma, and nematodes, (ROS) and reactive nitrogen species (RNS) levels, and In plants, melatonin metabolism encompasses a series
  8. Soil Nematodes as an Indicator of the Efficiency of Hydrophytic Treatment Plants with Vertical Wastewater Flow M Bagińska, T Warężak, W Romaniuk, D Kozacki… - …, 2025 - researchgate.net Tuesday 31 December 2024 Plant beds are abundantly populated by bacteria participating in key organic matter decomposition processes and nitrogen to the digestion and metabolism of the bacterial
  9. Understanding the dynamic A Habteweld¹, M Kantor, C Kantor - Plant Parasitic Nematode …, 2025 - books.google.com Thursday 23 January 2025 (rhizosphere bacteria) and inside plant roots (endophytic bacteria) on both plant development and metabolism through the the movement of nitrogen-fixing bacteria to the
  10. 3 Omics' Approach to Discern the Functional Diversity of Fungi in Plants A Mukherjee, GB Anam, YH Ahn - … of Medicinal Plants, 2025 - books.google.com Saturday 18 January 2025 Microorganismplant interactions in nitrogen fixation, improve our understanding of plant microbes and their -related grapevine plant woods carbohydrate metabolism (
  11. Soil biological health assessment based on nematode communities under maize and peanut intercropping S Liang, C Feng, N Li, Z Sun, Y Li, X Zhang… - Ecological …, 2024 - Springer Monday 11 November 2024 And plant parasitic nematode abundance, microbial the peak period of interaction between the intercropped ammonium nitrogen content and the nematode enrichment
  12. Soybean cyst nematode proliferation is slowed by local cyst bacteria M Hussain, P Xuan, Y Xin, H Ma, Y Zhou, S Wen… - 2024 - researchsquare.com Friday 26 July 2024 Soybean is an important food crop also used for biofuel production and nitrogen and that specific microbial communities targeting plant-parasitic nematodes could be
  13. lant Parasitic Nematodes: A Major Constraint to Pulses Production and Their Management Options$ B Singh - Indian Journal of Plant Protection - epubs.icar.org.in Friday 10 January 2025 By fixing atmospheric nitrogen through nematodes and promote antagonistic microbial activity. Many biocontrol agents are effective against plant parasitic nematodes
  14. … sp. 30702 composite chitosan alleviates continuous cropping obstacles in Chinese yam by improving rhizospheric soil microbial environment: A field study in … H Fan, R Zhang, J Lu, M Fu, A Waheed, X Liu… - … Technology & Innovation, 2025 - Elsevier Saturday 03 August 2024 Plant, yet its cultivation faces increasing challenges, particularly due to pathogenic community, while available nitrogen and root-knot nematodes significantly affect the
  15. … .. NCHULUS RENIFORMIS AND ASSOCIATED POPULATIONS OF PREDACIOUS AND SAPROPHYTIC ARTHROPODS AND MICROPHAGOUS NEMATODES T BADRA, MI MOHAMED - INDIAN JOURNAl OF NIMA TOIO - epubs.icar.org.in Tuesday 31 December 2024 In controlling nematode populations, plant growth was of associated microorganisms before experimentation. pots, each at the rate of 108kg nitrogen/ha, while one set

Elservier Scopus

Effect of Plant-Based Diets on Energy Metabolism and Metabolic Functions Karademir E. Current Nutrition Reports, volume 14 Saturday 15 November 2025
Discovery and characterisation of terpenoid biosynthesis enzymes from Daphniphyllum macropodum Eljounaidi K. BMC Plant Biology, volume 25 Friday 14 November 2025
Construction and analysis of a cell factory for terpenoid biosynthesis in Pichia pastoris via metabolic engineering and metabolomics Sun, Chenfan, Ye, Cuifang, Li, Xiaoqian, Xu, Jiabin, Yu, Huiru, Gao, Jucan, Guan, Chengran, Cheng, Jintao Synthetic and Systems Biotechnology, volume 11, pages 68-75 Tuesday 11 November 2025 Terpenoids are widely distributed in nature and have various applications in health products, pharmaceuticals, and fragrances. Despite the tremendous potential of terpenoids, traditional production methods such as plant extraction and chemical synthesis face challenges in meeting current market demands. With the developments in synthetic biology an... Terpenoids are widely distributed in nature and have various applications in health products, pharmaceuticals, and fragrances. Despite the tremendous potential of terpenoids, traditional production methods such as plant extraction and chemical synthesis face challenges in meeting current market demands. With the developments in synthetic biology and metabolic engineering, it has become feasible to construct efficient microbial cell factories for large-scale production for terpenoids. In this work, using the yeast Pichia pastoris as the host cell, a "plug-and-play" cell factory for universal terpenoid production was constructed by enhancing the expression of the MVA pathway for common precursor synthesis and reducing branch pathway diversion strategies. We have successfully and efficiently synthesized β-elemene, β-farnesene, (+)-valencene, (−)-α-bisabolol by this cell factory. Furthermore, by analyzing metabolites in different engineered strains in terms of system biology, it was discovered that an increase in key protein copy numbers enhanced the synthesis of arginine and other metabolic pathways. The robustness of the strains and the tightly regulated metabolic network constrain rational metabolic engineering transformations. These data provide important clues for the modification and optimization of production strains.
Diterpenoids from the brown alga Dictyota dichotoma with nematicidal activity against the plant parasitic nematode Aphelenchoides besseyi Iida, Manami, Nehira, Tatsuo, Kato, Aki, Hoshino, Shigeru, Ômura, Hisashi, Ohta, Shinji Phytochemistry, volume 242 Monday 10 November 2025 Three previously undescribed diterpenoids, designated amijial (1), dictyoepoxyperoxide (2), and hydroperoxyacetyldictyolal (3), were isolated from the brown alga Dictyota dichotoma along with eight known diterpenoids. Structural analysis revealed that 1 features a unique xenicane-related skeleton with a cyclic hemiacetal structure. The nematicidal ... Three previously undescribed diterpenoids, designated amijial (1), dictyoepoxyperoxide (2), and hydroperoxyacetyldictyolal (3), were isolated from the brown alga Dictyota dichotoma along with eight known diterpenoids. Structural analysis revealed that 1 features a unique xenicane-related skeleton with a cyclic hemiacetal structure. The nematicidal activity of the isolated compounds was evaluated against the plant-parasitic nematode Aphelenchoides besseyi. Compounds bearing the α,β-unsaturated 1,4-dialdehyde structural motif exhibited higher activity.
Copper homeostasis: Crosstalk with plant secondary metabolism and stress responses Akhtar, Muhammad Tanveer, Lu, Zhaogeng, Ren, Shi-xiong, Zou, He-lin, Noor, Iqra, Jin, Biao Plant Science, volume 362 Sunday 09 November 2025 Copper (Cu) is an essential micronutrient for plants that functioning as a cofactor in numerous enzymes. However, it becomes toxic in excess, necessitating homeostatic mechanisms. In this review, we synthesize current knowledge of the Cu uptake, transport, and homeostasis in plants, and examine the Cu-mediated regulation of plant... Copper (Cu) is an essential micronutrient for plants that functioning as a cofactor in numerous enzymes. However, it becomes toxic in excess, necessitating homeostatic mechanisms. In this review, we synthesize current knowledge of the Cu uptake, transport, and homeostasis in plants, and examine the Cu-mediated regulation of plant secondary metabolism. This review outlines the forms of Cu present in soils and plant systems and describes how roots acquire Cu (predominantly as Cu²⁺, which is then reduced to Cu⁺ at the root surface) via high-affinity transporters. Within the plant, the Cu uptake and distribution are mediated by a network of membrane transporters, chaperones, and storage molecules. These components ensure an adequate supply to essential cuproproteins while preventing toxicity. Molecular regulatory mechanisms, notably the SQUAMOSA Promoter Binding Protein-Like 7 (SPL7) transcription factor and Cu-responsive microRNAs such as miR397, miR398, and miR408, regulate Cu concentration in plants and modulate gene expression to maintain homeostasis under fluctuating Cu availability. Cu availability significantly influences the secondary metabolite biosynthesis. As a cofactor of key enzymes such as polyphenol oxidases and laccases, Cu affects the production of phenolics (including lignin), flavonoids, and other defensive secondary metabolites. Adequate Cu nutrition thereby enhances plant defense responses by fortifying cell walls, supporting antioxidant enzymes, and promoting the synthesis of antimicrobial compounds. Finally, we highlight the practical applications of Cu management strategies, such as optimizing foliar Cu supplementation and breeding for Cu-efficient genotypes, to enhance stress resilience, yield stability, and the nutritional quality of crops.
Germplasm Evaluation in Chickpea for Resistance to Plant Parasitic Nematodes Khan Z. Methods in Molecular Biology, volume 2966, pages 293-304 Friday 07 November 2025
Terpenoid-Based Inhibition of SQLE: Mechanistic Computational and Experimental Insights into Targeting Cholesterol Biosynthesis Kamel E.M. Journal of Computational Biophysics and Chemistry, volume 25, pages 853-874 Thursday 06 November 2025
Plant cold acclimation and its impact on sensitivity of carbohydrate metabolism Adler S.O. Npj Systems Biology and Applications, volume 11 Tuesday 04 November 2025
Tackling the plant parasitic nematode Meloidogyne enterolobii: Challenges and strategies for control in relevant crops de Oliveira Costa S.N. Tropical Plant Pathology, volume 50 Monday 03 November 2025
The plant epigenome governed by nutrients and metabolism Nie, Xuerui, Sheen, Jen, Ye, Ruiqiang Current Opinion in Plant Biology, volume 88 Sunday 02 November 2025 Nutrients are essential regulators of growth and development across all life forms, serving not only as energetic resources and structural building blocks but also as dynamic signals that govern cell proliferation, metabolism, growth and development. Nutrients and metabolic processes orchestrate plant developmental programs and p... Nutrients are essential regulators of growth and development across all life forms, serving not only as energetic resources and structural building blocks but also as dynamic signals that govern cell proliferation, metabolism, growth and development. Nutrients and metabolic processes orchestrate plant developmental programs and plasticity via the coordination with dynamic changes in the epigenomic landscape, which is fundamental for governing gene expression programs and developmental transitions in multicellular organisms. In this review, we explore the interplay between nutrition, metabolism, and epigenetic reprogramming in plants, with a particular focus on the novel mechanisms, including nuclear localized metabolic enzymes, moonlighting functions of metabolic enzymes, epigenetic regulators as metabolic sensors, and nutrient sensing and signaling pathways. Elucidating these mechanisms holds significant implications for understanding plant growth and development and improving crop yield and quality.

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